Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp136 | Obesity | ECE2016

A novel human fetal brown stem cell functional model to study brown adipogenesis

Franco Alessandra Di , Guasti Daniele , Squecco Roberta , Mazzanti Benedetta , Rossi Francesca , Idrizaj Eglantina , Gallego-Escuredo Jose , Villarroya Francesc , Bani Daniele , Forti Gianni , Vannelli Gabriella Barbara , Luconi Michaela

The potential therapeutic applications of targeting brown adipose tissue open new clinical avenues in fighting against metabolic pathologies. However, due to the limited brown depots in adult humans, dramatically reduced after birth, solid cell models to study human brown adipogenesis and its pathophysiological regulation are urgently needed.In our study, we characterized a novel human model of brown adipose stem cells, hfB-ASC, derived from fetal inters...